个人简介
教育经历
2003年于湘潭大学获学士学位；2010年于中国科学院化学研究所获博士学位。2010年8月至2012年8月在新加坡南洋理工大学做博士后研究，2012年10月加入中国科学院化学研究所，任助理研究员。2013年11月至今在买球最好的网站(中国)有限公司任教。
工作经历
研究方向
1、过渡金属催化的不对称催化反应研究
2、新型手性膦配体的合成及应用
3、催化反应在药物中间体及生物活性分子合成中的应用
代表成果
1.Cai You, Shuailong Li, Xiuxiu Li,Hui Lv*, Xumu Zhang*, Enantioselective Rh-Catalyzed Anti-Markovnikov Hydroformyla-tion of 1,1-Disubstituted Allylic Alcohols and Amines: An Efficient Route to Chiral Lactones and Lactams,ACS Catal.2019, 9, 8529-.
2.ShuailongLi, Zhuangxing Li, Cai You,Hui Lv*, Xumu Zhang, Recent Advances in Asymmetric Hydroformylation,Chinese Journal of Organic Chemistry,2019, 39, 1568-1582. (In Chinese)
3.Xiuxiu Li，Cai You，Jiaxin Yang, Shuailong Li, Dequan Zhang,Hui Lv*, Xumu Zhang*，Asymmetric Hydrocyanation of Alkenes without HCN，Angew. Chem. Int. Ed.2019,58, 10928.
4.Xu Deng, Li-Yang Shi, Jialing Lan, Yuqing Guan, Xiaoyong Zhang,Hui Lv*, Lung Wa Chung*, Xumu Zhang*, Enantioselective Rhodium-Catalyzed Cycloisomerization of 1,6-Allenynes to access 5/6-Fused Bicyclo[4.3.0]nonadienes,
Nat. Commun.,2019,10, 949.
5.Yu-Qing Guan, Zhengyu Han, Xiuxiu Li, Cai You, Xuefeng Tan,Hui Lv*, Xumu Zhang, A Cheap Metal for a Challenging Task: Nickel-Catalyzed Highly Diastereo- and Enantioselective Hydrogenation of Tetrasubstituted Fluorinated Enamides,Chem. Sci.2019, 256-259.
6.Jiao Long, Liyang Shi, Xiong Lia,Hui Lv*, Xumu Zhang*, Rhodium-Catalyzed Highly Regio- and Enantioselective Hydrogenation of Tetrasubstituted Allenyl Sulfones: An Efficient Access to Chiral Allylic Sulfones，Angew. Chem. Int. Ed.2018,57,13248-13251
7.Jiao Long, Wenchao Gao, Yuqing Guan,Hui Lv*, Xumu Zhang, Nickel-catalyzed Highly Enantioselective Hydrogenation of β-Acetylamino Vinylsulfones: An Efficient Access to Chiral β‑Amido Sulfones，Org. Lett.,2018，20, 5914–5917.
8.Cai You, Shuailong Li, Xiuxiu Li, Jialing Lan, Yuhong Yang, Lung Wa Chung, Hui Lv,* Xumu Zhang*, Design and Application of Hybrid Phosphorus Ligands for Enanti-oselective Rh-Catalyzed Anti-Markovnikov Hydroformylation of Unfunctionalized 1,1-Disubstituted Alkenes,J. Am. Chem. Soc.,2018,140, 4977–4981.
9.Cai You, Xiuxiu Li, Yuhong Yang, Yu-Sheng Yang, Xuefeng Tan, Shuailong Li, Biao Wei,Hui Lv*, Lung-Wa Chung*, Xumu Zhang*,Silicon-oriented regio- and enantioselective rhodium-catalyzed hydroformylation,Nat. Commun.,2018,9, 2045
10.Xiuxiu Li, Cai You, Yusheng Yang,Yuhong Yang, Pan Li, Guoxian Gu, Lung Wa Chung,Hui Lv*, Xumu Zhang*, Rhodium-catalyzed asymmetric hydrogenation of β-cyanoacrylate esters with the assistance of a single hydrogen bond in a precise position,Chem. Sci.,2018,9, 1919-1924
11.Zhichao Xiong, Chengfeng Pei, Peng Xue,Hui Lv*, Xumu Zhang*, Highly Enantioselective Transfer Hydrogenation of Racemica-Substitutedb-keto SulfonamidesviaDynamic Kinetic Resolution,Chem. Commun.2018,54, 3883-3886.
12.Xiuxiu Li, Cai You, Shuailong Li,aHui Lv*,Xumu Zhang*, Nickel-Catalyzed Enantioselective Hydrogenation of β-(acylamino)-acrylates: Synthesis of Chiral β-Amino Acid Derivatives,Org. Lett.,2017, 19, 5130-5133.
13.Wenchao Gao,Hui Lv*, Tonghuan Zhang*, Yuhong Yang, Lung Wa Chung*, Yun-Dong Wu, Xumu Zhang*, Nickel-Catalyzed Asymmetric Hydrogenation of ß-Acylamino Nitroolefins: An Efficient Approach to Chiral Amines,Chem. Sci.,2017,8, 6419-6422.
14.Hailong Yang, Erfei Wang, Ping Yang,Hui Lv,* and Xumu Zhang,* Pyridine-directed Asymmetric Hydrogenation of 1,1-Diarylalkenes,Org. Lett.,2017,19, 5062–5065
15.Xu Deng, Yuqing Guan, Ningning Huo, Yajing Wang,Hui LV*, Xumu Zhang, An Efficient and Modular Route to C3*-TunePhos-Type Ligands,Synthesis2017,49, 3726.
16.Wenchao Gao,Hui Lv*, Xumu Zhang*, Rh/DuanPhos-Catalyzed Asymmetric Hydrogenation of β-Acetylamino Vinylsulfides: An Approach to Chiral β-Acetylamino Sulfides,Org. Lett.,2017,19, 2877-2880.
17.Yu-Qing Guan, Min Gao, Xu Deng,Hui Lv*, Xumu Zhang*, Rhodium-catalyzed Asymmetric Hydrogenation of Tetrasubstituted β-acetoxy-α-enamido Esters and Efficient Synthesis of Droxidopa,Chem.Comm.2017,53, 8136-8139.
18.Xiuxiu Li, Cai You, Yusheng Yang, Fangyuan Wang, Shuailong Li,Hui Lv*, Xumu Zhang, Rhodium-catalyzed enantioselective hydrogenation of α-amino acrylonitriles: an efficient approach to synthesizing chiral α-amino nitriles,Chem.Comm.2017,53, 1313-1316.
19.Biao Wei, Caiyou Chen, Cai You,Hui Lv*,Xumu Zhang*, Efficient synthesis of (S,R)- Bn-Yanphos and Its Application in Asymmetric Hydroformylation of vinyl heteroarenes,Org. Chem. Front.2017,4, 288-291.
20.Xiuxiu Li, Cai You, Hailong Yang, Jinteng Che, Pengyu Chen,Hui Lv*,Xumu Zhang*, Highly Enantioselective Rhodium-Catalyzed Hydrogenation of Tetrasubstituted Cyclic Enamides: Efficient Access to Chiral Cycloalkylamines Derivatives,Adv.Synth. Catal.2017, 359,597–602.
21.Liyang Shi, Xuefeng Tan, Jiao Long, Xiong Xiong, Song Yang, Peng Xue,Hui Lv,*Xumu Zhang*, Direct Catalytic Hydrogenation of Simple Amides: A Highly Efficient Approach From amides to Amines and Alcohols,Chem. Eur. J.2017,23, 546-548.
22.Liyang Shi, Biao, Wei, Xuguang Yin, Peng, Xue,Hui Lv*, Xumu Zhang*, Rh-Catalyzed Asymmetric Hydrogenation of alpha-Substituted Vinyl Sulfones: An Efficient Approach to Chiral Sulfones,Org. Lett.2017,19, 1024-1027.
23.Caiyou Chen, Shicheng Jin, Zhefan Zhang, Heng Wang, Xinrui Wang, Kai Zhang,Hui Lv,*Xiu-Qin Dong,* and Xumu Zhang*, Rhodium/Yanphos-catalyzed asymmetric interrupted intramolecular hydroaminomethylation of tans-1, 2，disubstituted alkenes: efficient synthesis of chiral pyrrolidinones and pyrrolidines,J. Am. Soc. Chem.2016,138, 9017-9020.
24.Qingli Wang, Wenchao Gao,Hui Lv,*Xumu Zhang*, Enantioselective synthesis ofb-substituted Chiral Allylic Amines via Rh-Catalyzed Asymmetric Hydrogenation,Chem.Comm.2016,52, 11850-11853.
25.Fangyuan Wang, Xuefeng Tan,Hui Lv*, and Xumu Zhang*，New Ruthenium Complexes Based on Tetradentate Bipyridine Ligands for Catalytic Hydrogenationof Esters，Chem.-asian J.,2016,11, 2103-2106.
26.Guozhen Wang, Xuefeng Tan,Hui Lv, Mengmeng Zhao, Min Wu, Jinping Zhou, Xumu Zhang*, Lina Zhang*, Highly Selective Conversion of Cellobiose and Cellulose to Hexitols by Ru-Based Homogeneous Catalyst under Acidic Condition, Ind. Eng. Chem. Res.,2016,55,5263-5270.
27.Cai You, Biao Wei, Xiuxiu Li, Yusheng Yang, Yue Liu,Hui Lv,*and Xumu Zhang*, Rhodium-Catalyzed Desymmetrization by Hydroformylation of Cyclopentenes: Synthesis of Chiral Carbocyclic Nucleosides,Angew. Chem. Int. Ed.2016, 55, 6511-6514.
28.Xu Deng, Shao-Fei Ni, Zheng-Yu Han, Yu-Qing Guan,Hui Lv, Li Dang,* and Xu-Mu Zhang*, Enantioselective Rhodium-Catalyzed Cycloisomerization of (E)-1,6-Enynes,Angew. Chem. Int. Ed.2016,55, 6295-6298
29.Xuefeng Tan, Guozhen Wang, Ziyue Zhu, Conghui Ren, Jinping Zhou,Hui Lv, Xiaoyong Zhang, Lung Wa Chung,*Lina Zhang,* Xumu Zhang*, Hydrogenation of Aldehydes Catalyzed by an Available Ruthenium Complex,Org. Lett.2016, 18, 1518-1521.
30.Wenchao Gao, Qingli Wang, Yun Xie,Hui Lv*, and Xumu Zhang*, Rhodium-catalyzed Asymmetric Hydrogenation of α-Dehydroamino Ketones: AGeneral Approach to Chiralα-amino Ketones,Chem.-asian J.,2016,11, 231-233.
31.Hailong Yang, Ningning Huo, Ping Yang, Hao Pei,Hui Lv*, Xumu Zhang*, Rhodium catalyzed asymmetric hydrogenation of 2-pyridine ketones,Org. Lett.2015,17, 4144-4147.
32.Xuefeng Tan, Qingli Wang, Yuanhua Liu, Fangyuan Wang,Hui Lv*, Xumu Zhang*, A New Designed Hydrazine Group-contained Ruthenium Complex Used for Catalytic Hydrogenation of Esters,Chem. Comm.,2015,51, 12193-12196.
33.Jun Jiang, Wenxin Lu,Hui Lv*, Xumu Zhang*, Highly Efficient Synthesis of Chirala-CF3 Amines via Rh-Catalyzed Asymmetric Hydrogenation,Org. Lett.2015,17, 1154-1156.
34.Jianjian Ji, Caiyou Chen, Jiayu Cai, Xinrui Wang, Kai Zhang, Liyang Shi,Hui Lv*, XumuZhang*,Highly Enantioselective Synthesis of Non-natural Aliphatica-Amino Acids via Asymmetric Hydrogenation,Org. Biomol. Chem.,2015,13, 7624.
35.Jingjing Meng, Min Gao,Hui Lv*, Xumu Zhang*, Highly Enantioselective Hydrogenation of Ortho-Alkoxy Tetrasubstituted Catalyzed by a Rh/(R,S)-JosiPhos Catalyst,Org. Lett.2015,17, 1842-1845.
36.Xuefeng Tan, Yan Wang, Yuanhua Liu, Fangyuan Wang, Liyang Shi, Ka-Ho Lee, Zhenyang Lin,Hui Lv*, and Xumu Zhang* Highly Efficient Tetradentate Ruthenium Catalyst for Ester Reduction: Especially for Hydrogenation of Fatty Acid Esters.Org. Lett.2015,17,454-457.
37.Min Gao, Jing-jing Meng,Hui Lv*, and Xumu Zhang*, Highly Regio- and Enantioselective Synthesis ofg,d-Unsaturated Amido Esters by Catalytic Hydrogenation of Conjugated Enamides.Angew. Chem. Int. Ed.2015,54, 1885-1887.
38.Qingli Wang, Wenhua Huang, Haoquan Yuan, Qin Cai, Liming Chen,Hui Lv*, Xumu Zhang*, Rhodium-Catalyzed Enantioseletive Hydrogenation of Tetrasubstituted α-Acetoxy β-Enamido Esters: a New Ap-proach to Chiral α-Hydroxyl-β-Amino Acid derivatives.J. Am. Chem. Soc.2014,136, 16120−16123.
39.Caiyou Chen, Pan Li, Zhoumi Hu, Heng Wang, Huaisu Zhu, Xinquan Hu, Yan Wang,Hui Lv*, Xumu Zhang*, Synthesis and Application of a New Triphosphorus Ligand for Regioselective Linear Hydroformylation: A Potential Way for the Stepwise Replacement of PPh3 for Industrial Use,Org. Chem. Front.2014,1, 947.
40.Ming Zhou, Tanglin Liu, Min Cao, Zejian Xue,Hui Lv*, Xumu Zhang*, Highly Enantioseletive Synthesis of Chiral Cyclic Allylic Amines via Rh-catalyzed Asymmetric Hydrogenation，Org. Lett.2014，16, 3484-3487.
